Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCA | P17252 | 1/20 | 0.40 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.32 |
| ▸ | NR1I2 | O75469 | 4/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GLP1R | P43220 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12429151 | 0.92 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL803754 | 0.92 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL12428525 | 0.92 | PRKCA (0.42) | PRKCAMMP12SCN9ANR1I2 | |
| SCHEMBL10283575 | 0.91 | PRKCA (0.42) | PRKCAMMP12SCN9AKDM4CNR1I2 | |
| SCHEMBL12429322 | 0.90 | PRKCA (0.47) | PRKCAMMP12SCN9ANR1I2KCNH2 | |
| SCHEMBL10283578 | 0.90 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL12428570 | 0.90 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL12428553 | 0.90 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL10283736 | 0.90 | PRKCA (0.43) | PRKCAMMP12SCN9ANR1I2DPP4 | |
| SCHEMBL10283613 | 0.90 | PRKCA (0.40) | PRKCAMMP12SCN9ANR1I2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |
| US-7977331-B1 | Tetracyclic fused heterocyclic compound and use thereof as HCV polymerase inhibitor | JAPAN TOBACCO INC. (JP) | 2011-07-12 | — | — | US | disclosed |