Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 3/20 | 0.46 |
| ▸ | MAOB | P27338 | 3/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22049279 | 0.85 | MEN1 (0.59) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL21468535 | 0.82 | S100B (0.38) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL10229442 | 0.81 | HTR2C (0.40) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL2571297 | 0.80 | MAOB (0.65) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL3439485 | 0.79 | MAOB (0.49) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL24869723 | 0.78 | MEN1 (0.77) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL30875685 | 0.78 | MEN1 (0.77) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL13928803 | 0.77 | AR (0.52) | MEN1KMT2AGAASMN1; SMN2MAOA | |
| SCHEMBL2207784 | 0.76 | NOTUM (0.57) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL29963196 | 0.76 | NOTUM (0.57) | SMN1; SMN2KDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981903-B2 | 2-[2-{phenylamino}-1H-pyrrolo[2,3-D]pyrimidin-4-yl)amino] benzamide derivatives as IGF-1R inhibitors for the treatment of cancer | GLAXOSMITHKLINE LLC (US) | 2011-07-19 | — | — | US | disclosed |