Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 9/20 | 0.52 |
| ▸ | PKM | P14618 | 2/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.49 |
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PLG | P00747 | 1/20 | 0.49 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17209386 | 1.00 | FOLH1 (0.52) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL12984654 | 0.81 | PKM (0.49) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL17209334 | 0.81 | PLCG1 (0.44) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL17209387 | 0.81 | PLCG1 (0.44) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL24220346 | 0.79 | FOLH1 (0.54) | FOLH1PRSS1PRSS2PRSS3TPSAB1 | |
| SCHEMBL4968230 | 0.77 | F2 (0.73) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL19751698 | 0.77 | F2 (0.73) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL15216220 | 0.77 | F2 (0.73) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL19017236 | 0.77 | F2 (0.73) | FOLH1PKMPRSS1PRSS2PRSS3 | |
| SCHEMBL15279174 | 0.77 | F2 (0.66) | FOLH1PKMPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2351777-B1 | ANTI-MUC1 ANTIBODY | SHIONOGI & CO (JP) | 2015-10-28 | — | — | EP | disclosed |
| EP-2351777-A1 | ANTI-MUC1 ANTIBODY | Shionogi & Co., Ltd. (JP) | 2011-08-03 | — | — | EP | disclosed |