Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 8/20 | 0.54 |
| ▸ | PLG | P00747 | 1/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.53 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.53 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.53 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.53 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PSEN1 | P49768 | 3/20 | 0.47 |
| ▸ | PSEN2 | P49810 | 3/20 | 0.47 |
| ▸ | APH1B | Q8WW43 | 3/20 | 0.47 |
| ▸ | NCSTN | Q92542 | 3/20 | 0.47 |
| ▸ | APH1A | Q96BI3 | 3/20 | 0.47 |
| ▸ | PSENEN | Q9NZ42 | 3/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.45 |
| ▸ | NOXO1 | Q8NFA2 | 1/20 | 0.45 |
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24220342 | 0.87 | FOLH1 (0.58) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24220343 | 0.87 | FOLH1 (0.58) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24220332 | 0.82 | FOLH1 (0.56) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24601730 | 0.79 | FOLH1 (0.70) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24601734 | 0.79 | FOLH1 (0.70) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL17209386 | 0.79 | FOLH1 (0.52) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL12429627 | 0.79 | FOLH1 (0.52) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24601548 | 0.78 | FOLH1 (0.70) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL12984654 | 0.78 | PKM (0.49) | FOLH1PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL24220333 | 0.77 | FOLH1 (0.68) | FOLH1PLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220026420-A1 | MOLECULES AND METHODS FOR IMPROVED IMMUNODETECTION OF SMALL MOLECULES SUCH AS HISTAMINE | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-27 | — | — | US | disclosed |