SCHEMBL1243019

SCHEMBL1243019

C=CCCCSCCCC=C

nearest known ligand 0.45

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
TSHR P16473 3/20 0.45
ALOX5 P09917 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
TRPA1 O75762 4/20 0.35
ABCC4 O15439 1/20 0.35
MAPT P10636 1/20 0.35
CYP3A4 P08684 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1240083 0.90 TSHR (0.46) ALDH1A1TSHRALOX5SMN1; SMN2TRPA1
SCHEMBL1017964 0.89
SCHEMBL19644551 0.88 TSHR (0.50) ALDH1A1TSHRALOX5SMN1; SMN2TRPA1
SCHEMBL19644556 0.88 TSHR (0.50) ALDH1A1TSHRALOX5SMN1; SMN2TRPA1
SCHEMBL1454741 0.87
SCHEMBL11328377 0.85
SCHEMBL1017004 0.85
SCHEMBL11330321 0.83 TSHR (0.65) ALDH1A1TSHRMAPT
SCHEMBL1020050 0.81 TSHR (0.39) ALDH1A1TSHRTRPA1ABCC4MAPT
SCHEMBL2122053 0.80 ALDH1A1 (0.45) ALDH1A1TSHRALOX5SMN1; SMN2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111876748-A Metal sulfide thin film based on organic sulfur precursor and preparation method thereof 北京大学深圳研究生院 2020-11-03 CN claimed
CN-119684341-A Double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2025-03-25 CN disclosed
EP-4435013-A2 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING Dow Global Technologies LLC (US) 2024-09-25 EP disclosed
EP-3519474-B1 PROCESS FOR PREPARING MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING DOW GLOBAL TECHNOLOGIES LLC (US) 2024-09-25 EP disclosed
EP-3519456-B1 CAPPED MULTI- OR DUAL-HEADED COMPOSITIONS USEFUL FOR CHAIN SHUTTLING AND PROCESS TO PREPARE THE SAME DOW GLOBAL TECHNOLOGIES LLC (US) 2024-07-03 EP disclosed
EP-3732211-B1 CAPPED DUAL-HEADED ORGANOALUMINUM COMPOSITIONS DOW GLOBAL TECHNOLOGIES LLC (US) 2024-05-22 EP disclosed
CN-111433235-B Capped double-ended organoaluminum compositions 陶氏环球技术有限责任公司 2023-06-13 CN disclosed
CN-109952324-B Blocked multi-or double-headed compositions suitable for chain shuttling and methods of making the same 陶氏环球技术有限责任公司 2023-06-09 CN disclosed
US-11613600-B2 Capped dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2023-03-28 US disclosed
US-11492450-B2 Dual-headed organoaluminum compositions DOW GLOBAL TECHNOLOGIES LLC (US) 2022-11-08 US disclosed
WO-2017205713-A1 ALIPHATIC POLYSULFONES WITH IMPROVED MECHANICAL INTEGRITY UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2017-11-30 WO disclosed
EP-3243846-A2 MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies Llc (US) 2017-11-15 EP disclosed
EP-2459598-B1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2017-10-18 EP disclosed
CN-102498133-B Bid-or multi-head chain shuttling agents and their use for the preparation of block copolymers DOW GLOBAL TECHNOLOGIES INC 2013-10-30 CN disclosed
US-8501885-B2 Dual- or multi-headed chain shuttling agents and their use for preparation of block copolymers DOW GLOBAL TECHNOLOGIES, LLC (US) 2013-08-06 US disclosed
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES LLC (US) 2012-06-28 US disclosed
CN-102498133-A Bid-or multi-head chain shuttling agents and their use for the preparation of block copolymers DOW GLOBAL TECHNOLOGIES INC 2012-06-13 CN disclosed
EP-2459598-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS Dow Global Technologies LLC (US) 2012-06-06 EP disclosed
WO-2011016991-A2 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR THE PREPARATION OF BLOCK COPOLYMERS DOW GLOBAL TECHNOLOGIES INC. (US) 2011-02-10 WO disclosed
US-4683301-A BACTERICIDES BRISTOL-MYERS COMPANY (US) 1987-07-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11613600-B2 Capped dual-headed organoaluminum compositions CAPG, C5, CDS2 ALDH1A1 2097/4885TSHR 4645/4885ALOX5 285/4885
US-20120165486-A1 DUAL- OR MULTI-HEADED CHAIN SHUTTLING AGENTS AND THEIR USE FOR PREPARATION OF BLOCK COPOLYMERS MSN, COASY, MCM7 ALDH1A1 3614/4885TSHR 4812/4885ALOX5 606/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.