⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739 | 1.00 | — | — | |
| SCHEMBL11708371 | 1.00 | HCAR2 (0.46) | — | |
| SCHEMBL1740 | 1.00 | — | — | |
| SCHEMBL11707587 | 0.79 | — | — | |
| SCHEMBL11050866 | 0.78 | TSHR (0.37) | — | |
| SCHEMBL2326348 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL2326345 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL2326353 | 0.77 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL15459193 | 0.77 | — | — | |
| SCHEMBL24793666 | 0.77 | NPSR1 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250382304-A1 | HETEROAROMATIC MACROCYCLIC ETHER CHEMOTHERAPEUTIC AGENTS | NUVALENT INC (US) | 2025-12-18 | — | — | US | disclosed |
| US-12454530-B2 | Amido cyclohexane acid derivatives as LPA receptor inhibitors | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-10-28 | — | — | US | disclosed |
| US-20250188068-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-06-12 | — | — | US | disclosed |
| US-12275742-B2 | Heteroaromatic macrocyclic ether chemotherapeutic agents | NUVALENT, INC. (US) | 2025-04-15 | — | — | US | disclosed |
| US-20250066341-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2025-02-27 | — | — | US | disclosed |
| EP-4490150-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2025-01-15 | — | — | EP | disclosed |
| EP-4452965-A1 | CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | Chiesi Farmaceutici S.p.A. (IT) | 2024-10-30 | — | — | EP | disclosed |
| EP-4182301-B1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARM SPA (IT) | 2024-09-04 | — | — | EP | disclosed |
| WO-2023170025-A1 | AMIDO CYCLOPROPYL DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-09-14 | — | — | WO | disclosed |
| US-20230250093-A1 | AMIDO CYCLOHEXANE ACID DERIVATIVES AS LPA RECEPTOR INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2023-08-10 | — | — | US | disclosed |
| US-20150299383-A1 | FOAM COMPOSITIONS | AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) | 2015-10-22 | — | — | US | disclosed |
| US-8785442-B2 | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX, INC. (CN) | 2014-07-22 | — | — | US | disclosed |
| US-8785442-B2 | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX, INC. (CN) | 2014-07-22 | — | — | US | disclosed |
| US-8785442-B2 | Compound as antagonist of lysophosphatidic acid receptor, composition, and use thereof | CUREGENIX, INC. (CN) | 2014-07-22 | — | — | US | disclosed |
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX, INC. (CN) | 2014-01-30 | — | — | US | disclosed |
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX, INC. (CN) | 2014-01-30 | — | — | US | disclosed |
| US-20140031353-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX, INC. (CN) | 2014-01-30 | — | — | US | disclosed |
| WO-2012100436-A1 | COMPOUND AS ANTAGONIST OF LYSOPHOSPHATIDIC ACID RECEPTOR, COMPOSITION, AND USE THEREOF | CUREGENIX INC. (CN) | 2012-08-02 | — | — | WO | disclosed |
| US-7981950-B2 | Dispersant-encapsulated particulate solids | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2011-07-19 | — | — | US | disclosed |
| US-20070263050-A1 | Process | FUJIFILM IMAGING COLORANTS LIMITED (GB) | 2007-11-15 | — | — | US | disclosed |