Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11684067 | 0.92 | SMN1; SMN2 (0.36) | TSHRALDH1A1TP53HIF1AHSD17B10 | |
| SCHEMBL9119949 | 0.90 | HCAR2 (0.47) | TSHRALDH1A1ATMNPSR1HCAR2 | |
| SCHEMBL11593363 | 0.90 | TSHR (0.47) | TSHRALDH1A1ATMNPSR1HCAR2 | |
| SCHEMBL9119943 | 0.90 | HCAR2 (0.47) | TSHRALDH1A1ATMNPSR1HCAR2 | |
| SCHEMBL10984499 | 0.86 | ATM (0.57) | TSHRALDH1A1ATMNPSR1HCAR2 | |
| SCHEMBL11585793 | 0.85 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL24793666 | 0.84 | NPSR1 (0.52) | ALDH1A1TP53HSD17B10ATMNPSR1 | |
| SCHEMBL1127387 | 0.84 | NPSR1 (0.52) | ALDH1A1TP53HSD17B10ATMNPSR1 | |
| SCHEMBL6570866 | 0.84 | NPSR1 (0.52) | ALDH1A1TP53HSD17B10ATMNPSR1 | |
| SCHEMBL10900619 | 0.83 | EPHX1 (0.58) | TSHRALDH1A1ATMHCAR2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4424336-A | Meat-curable mixture, which are stable on storage, of epoxide resin, 3-aminocrotonic acid derivatives and maleimide compound | CIBA-GEIGY CORPORATION (US) | 1984-01-03 | — | — | US | disclosed |
| US-4360655-A | Heat-curable mixtures, which are stable on storage, of epoxide compounds β-aminocrotonic acid derivatives and polyamine | CIBA-GEIGY CORPORATION (US) | 1982-11-23 | — | — | US | disclosed |
| US-4348511-A | POLYURETHANES MODIFIED WITH BETA-AMINOCROTONIC ACID DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1982-09-07 | — | — | US | disclosed |
| US-4291146-A | Heat-curable mixtures, which are stable on storage, of expoxide resins and β-aminocrotonic acid derivatives | CIBA-GEIGY CORPORATION (US) | 1981-09-22 | — | — | US | disclosed |
| US-4284752-A | Process for producing crosslinked unsaturated polymers by reaction of .beta. | CIBA-GEIGY CORPORATION (US) | 1981-08-18 | — | — | US | disclosed |
| US-4161580-A | Thermosetting mixtures of polyimide beta-amino crotonic acid derivative and polyamine which are stable on storage | CIBA-GEIGY CORPORATION (US) | 1979-07-17 | — | — | US | disclosed |
| US-4089845-A | Thermosetting mixtures which are stable on storage from polyimide and .beta. | CIBA-GEIGY CORPORATION (US) | 1978-05-16 | — | — | US | disclosed |