Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 9/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 9/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12374406 | 0.89 | MAPK1 (0.39) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL19197042 | 0.88 | LPL (0.50) | MAPK1LPLLIPGIRAK4 | |
| SCHEMBL26622502 | 0.86 | MAPK1 (0.38) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL13785154 | 0.84 | MAPK1 (0.37) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL19831182 | 0.81 | MAPK1 (0.35) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL26153576 | 0.79 | LPL (0.39) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL3690683 | 0.78 | CYP3A4 (0.43) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL20661095 | 0.78 | CYP3A4 (0.43) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL17752342 | 0.78 | JAK2 (0.34) | MAPK1LPLLIPGP2RX7 | |
| SCHEMBL24145540 | 0.77 | CYP1A2 (0.41) | LPLLIPGIRAK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981525-B2 | Naphthalene compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981525-B2 | Naphthalene compound and organic light-emitting device using the compound | CANON KABUSHIKI KAISHA (JP) | 2011-07-19 | — | — | US | disclosed |
| US-20080224603-A1 | NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2008-09-18 | — | — | US | disclosed |
| US-20080224603-A1 | NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | CANON KABUSHIKI KAISHA (JP) | 2008-09-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080224603-A1 | NAPHTHALENE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING THE COMPOUND | AHR, CRY1, NR2E3 | MAPK1 822/4885LPL 2237/4885LIPG 3815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.