Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 4/20 | 0.44 | |
| ▸ | MMP1 | P03956 | 4/20 | 0.39 |
| ▸ | MMP13 | P45452 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12433193 | 0.92 | PDF (0.43) | PDFMMP1MMP13 | |
| SCHEMBL12433194 | 0.88 | PDF (0.45) | PDFMMP1MMP13 | |
| SCHEMBL2210555 | 0.87 | PDF (0.44) | PDFMMP1MMP13 | |
| SCHEMBL5496476 | 0.85 | PDF (0.48) | PDFMMP1MMP13 | |
| SCHEMBL5496473 | 0.85 | PDF (0.48) | PDFMMP1MMP13 | |
| SCHEMBL12433195 | 0.85 | PDF (0.47) | PDFMMP1MMP13 | |
| SCHEMBL14282146 | 0.83 | PDF (0.64) | PDFMMP1MMP13 | |
| SCHEMBL14282151 | 0.82 | PDF (0.62) | PDFMMP1MMP13 | |
| SCHEMBL13333334 | 0.82 | PDF (0.43) | PDFMMP1MMP13 | |
| SCHEMBL14573452 | 0.82 | PDF (0.43) | PDFMMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912662-B1 | PEPTIDE DEFORMYLASE INHIBITORS | GLAXOSMITHKLINE LLC (US) | 2013-08-21 | — | — | EP | disclosed |
| US-7982053-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-07-19 | — | — | US | disclosed |
| US-7982053-B2 | Peptide deformylase inhibitors | GLAXOSMITHKLINE LLC (US) | 2011-07-19 | — | — | US | disclosed |
| US-20090239866-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-24 | — | — | US | disclosed |
| US-20090239866-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-09-24 | — | — | US | disclosed |
| WO-2007016364-A2 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090239866-A1 | PEPTIDE DEFORMYLASE INHIBITORS | PDF, PEPD, DPEP1 | PDF 1/4885MMP1 1612/4885MMP13 1748/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.