Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12387743 | 0.92 | KMT2A (0.42) | MAPK1KDM4ETSHRCYP2C19KMT2A | |
| SCHEMBL15613399 | 0.90 | KMT2A (0.43) | MAPK1KDM4ETSHRCYP2C19KMT2A | |
| SCHEMBL16790905 | 0.85 | KDM4E (0.52) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL23794346 | 0.85 | KDM4E (0.40) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL10311745 | 0.83 | MAPK1 (0.50) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL5157765 | 0.83 | KDM4E (0.55) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL23839876 | 0.83 | MAPK1 (0.39) | MAPK1KDM4EHIF1AMTNR1AMTNR1B | |
| SCHEMBL8404632 | 0.82 | KMT2A (0.39) | MAPK1KDM4ETSHRCYP2C19KMT2A | |
| SCHEMBL15613403 | 0.81 | KMT2A (0.45) | TSHRCYP2C19KMT2ACYP2D6CYP2C9 | |
| SCHEMBL16789572 | 0.81 | KMT2A (0.36) | MAPK1TSHRCYP2C19KMT2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | LUMIPHORE, INC. (US) | 2011-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110189088-A1 | RADIOPHARMACEUTICAL COMPLEXES | SLC39A3, SLC30A5, SLC40A1 | MAPK1 4867/4885KDM4E 3181/4885HIF1A 1411/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.