Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | MTNR1A | P48039 | 7/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 7/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16790905 | 0.97 | KDM4E (0.52) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL5179872 | 0.91 | KDM4E (0.46) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL16317805 | 0.91 | PAOX (0.47) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL20725629 | 0.89 | PAOX (0.52) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL474091 | 0.87 | ALDH1A1 (0.53) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL18307272 | 0.87 | KDM4E (0.48) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL12433198 | 0.87 | KDM4E (0.43) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL10937049 | 0.87 | PAOX (0.48) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL486581 | 0.84 | TDP1 (0.54) | KDM4EMAPK1HIF1AMTNR1AMTNR1B | |
| SCHEMBL8047064 | 0.84 | TSHR (0.52) | KDM4EMAPK1HIF1AMTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0762901-B9 | TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING | CIS BIO INT (FR) | 2007-01-17 | — | — | EP | claimed |
| EP-0684843-B1 | TECHNETIUM-99m LABELED PEPTIDES FOR DIAGNOSTIC IMAGING OF INFLAMMATION | DIATIDE INC (US) | 2006-05-10 | — | — | EP | claimed |
| EP-0762901-B1 | TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING | BERLEX INC (US) | 2006-04-19 | — | — | EP | claimed |
| EP-1583565-A1 | ENHANCED SCINTIGRAPHIC IMAGING AGENTS FOR IMAGING OF INFECTION AND INFLAMMATION | Schering AG (DE) | 2005-10-12 | — | — | EP | claimed |
| US-20050002861-A1 | Enhanced scintigraphic imaging agents for imaging of infection and inflammation | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2005-01-06 | — | — | US | claimed |
| EP-0775160-B1 | CYCLIC HEXAPEPTIDE SOMATOSTATIN ANALOGUES | DIATIDE INC (US) | 2004-08-18 | — | — | EP | claimed |
| WO-2004060409-A1 | ENHANCED SCINTIGRAPHIC IMAGING AGENTS FOR IMAGING OF INFECTION AND INFLAMMATION | SCHERING AG (DE) | 2004-07-22 | — | — | WO | claimed |
| EP-1437145-A1 | Enhanced scintigraphic imaging agents for imaging of infection and inflammation | Schering AG (DE) | 2004-07-14 | — | — | EP | claimed |
| EP-0804481-B1 | SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS | DIATIDE INC (US) | 2003-04-16 | — | — | EP | claimed |
| US-6241965-B1 | MEDICAL DIAGNOSTIC AND ANTITUMOR AGENTS | DIATIDE, INC. | 2001-06-05 | — | — | US | claimed |
| US-6074627-A | STABLE COMPLEX | DIATIDE, INC. (US) | 2000-06-13 | — | — | US | claimed |
| US-6019958-A | POLYBASIC COMPOUND HAVING A MOLECULAR WEIGHT FROM ABOUT 500 DALTONS TO ABOUT 15,000 DALTONS WITH A TECHNETIUM-99M BINDING MOIETY COVALENTLY LINKED TO THE COMPOUND; AND A POLYSULFATED GLYCAN HAVING A MOLECULAR WEIGHT OF AT LEAST ABOUT 1,000 | DIATIDE, INC. (US) | 2000-02-01 | — | — | US | claimed |
| US-5997844-A | Technetium-99m labeled peptides for imaging | DIATIDE, INC. (US) | 1999-12-07 | — | — | US | claimed |
| EP-0702570-B1 | TECHNETIUM-99m LABELED PEPTIDES FOR IMAGING INFLAMMATION | DIATIDE INC (US) | 1999-08-04 | — | — | EP | claimed |
| US-5932189-A | RADIOTHERAPY, RADIODIAGNOSIS PEPTIDES | DIATECH, INC. (US) | 1999-08-03 | — | — | US | claimed |
| US-5830856-A | RADIOLABELED SCINTIGRAPHIC IMAGING | DIATIDE, INC. (US) | 1998-11-03 | — | — | US | claimed |
| EP-0772460-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1997-05-14 | — | — | EP | claimed |
| WO-1995033496-A1 | RADIOLABELED COMPOUNDS FOR THROMBUS IMAGING | DIATECH, INC. (US) | 1995-12-14 | — | — | WO | claimed |
| WO-1995003330-A1 | SOMATOSTATIN DERIVATIVES AND THEIR RADIOLABELLED PRODUCTS | DIATECH, INC. (US) | 1995-02-02 | — | — | WO | claimed |
| WO-1995000553-A1 | RADIOLABELED SOMATOSTATIN-DERIVED PEPTIDES FOR IMAGING AND THERAPEUTIC USES | DIATECH, INC. (US) | 1995-01-05 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050002861-A1 | Enhanced scintigraphic imaging agents for imaging of infection and inflammation | SIGLEC7, CD209, SIGLEC9 | KDM4E 4063/4885MAPK1 2923/4885HIF1A 803/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.