Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 9/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 9/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 7/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12531878 | 0.83 | RAB9A (0.58) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2704695 | 0.83 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL3702836 | 0.83 | RAB9A (0.57) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL21654594 | 0.76 | ALOX5 (0.55) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL8437448 | 0.71 | RAB9A (0.46) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2829046 | 0.64 | KDM4E (0.61) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| SCHEMBL2829047 | 0.64 | KDM4E (0.61) | RAB9ANPC1SMN1; SMN2L3MBTL1TDP1 | |
| (Z)-1,2-Diphenylethene SCHEMBL22712863 | 0.63 | MAOB (0.73) | KMT2AALDH1A1MEN1ALOX5TRPA1 | |
| (Z)-1,2-Diphenylethene SCHEMBL9134296 | 0.63 | MAOB (0.73) | KMT2AALDH1A1MEN1ALOX5TRPA1 | |
| (Z)-1,2-Diphenylethene SCHEMBL21847984 | 0.63 | MAOB (0.73) | KMT2AALDH1A1MEN1ALOX5TRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |