Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.55 |
| ▸ | MIF | P14174 | 10/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | GLA | P06280 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.54 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.54 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12414854 | 0.88 | MAOA (0.58) | KDM4EGLAGAAALDH1A1HPGD | |
| SCHEMBL15082511 | 0.84 | HSD17B3 (0.59) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL15084994 | 0.82 | GPR55 (0.47) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL29066603 | 0.82 | ESR2 (0.61) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL220708 | 0.82 | HSD17B3 (0.65) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL30405545 | 0.82 | HSD17B3 (0.65) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL15084975 | 0.82 | POLB (0.58) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL9436016 | 0.82 | KDM4E (0.54) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL27844746 | 0.82 | GAA (0.58) | POLBHSD17B3MIFKDM4EMEN1 | |
| SCHEMBL6037595 | 0.81 | POLB (0.59) | POLBHSD17B3MIFKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9075014-B2 | pH-responsive fluorescent false neurotransmitters and their use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-07-07 | — | — | US | disclosed |
| US-9075014-B2 | pH-responsive fluorescent false neurotransmitters and their use | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2015-07-07 | — | — | US | disclosed |
| US-20130171664-A1 | PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-07-04 | — | — | US | disclosed |
| US-20130171664-A1 | PH-RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK | 2013-07-04 | — | — | US | disclosed |
| WO-2011094560-A1 | PH RESPONSIVE FLUORESCENT FALSE NEUROTRANSMITTERS AND THEIR USE | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2011-08-04 | — | — | WO | disclosed |