SCHEMBL12433600

SCHEMBL12433600

Cc1cc2sc3cc(C)c4ccccc4c3c2c2ccccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.49
MAPT P10636 3/20 0.49
POLB P06746 2/20 0.49
GAA P10253 2/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP1A2 P05177 5/20 0.46
GPR3 P46089 1/20 0.44
CYP2A6 P11509 3/20 0.40
TYMS P04818 1/20 0.38
MAOA P21397 1/20 0.37
MAOB P27338 1/20 0.37
HPGD P15428 2/20 0.36
RAB9A P51151 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
CYP2C19 P33261 1/20 0.36
TNKS2 Q9H2K2 1/20 0.36
BACE1 P56817 1/20 0.35
ALOX15 P16050 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11992362 0.90 ALDH1A1 (0.53) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL22941516 0.89 ALDH1A1 (0.42) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL12433615 0.89 ALDH1A1 (0.42) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL18810728 0.87 HSD17B10 (0.42) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL24614405 0.87 ALDH1A1 (0.42) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL23348094 0.86 ALDH1A1 (0.40) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL18810716 0.83 ALDH1A1 (0.41) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL15725992 0.83 ALDH1A1 (0.44) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL12433612 0.83 MAPT (0.41) ALDH1A1MAPTPOLBGAAMEN1
SCHEMBL18810727 0.78 CYP1A1 (0.42) ALDH1A1MAPTPOLBGAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9190622-B2 Hybrid ambipolar TFTs MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-9190622-B2 Hybrid ambipolar TFTs MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
WO-2012163464-A1 HYBRID AMBIPOLAR TFTS MERCK PATENT GMBH (DE) 2012-12-06 WO disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed