SCHEMBL12433612

SCHEMBL12433612

Cc1ccc2c(c1)sc1cc(C)c3ccccc3c12

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.41
MEN1 O00255 5/20 0.41
KMT2A Q03164 5/20 0.41
ALDH1A1 P00352 4/20 0.41
GAA P10253 4/20 0.41
POLB P06746 2/20 0.41
MCL1 Q07820 2/20 0.37
BCL2L1 Q07817 1/20 0.37
RAB9A P51151 6/20 0.37
SMN1; SMN2 Q16637 4/20 0.37
HPGD P15428 1/20 0.37
KIF11 P52732 1/20 0.37
CYP1A2 P05177 3/20 0.36
CYP2A6 P11509 1/20 0.36
PMM2 O15305 1/20 0.35
MPI P34949 1/20 0.35
PHOSPHO1 Q8TCT1 1/20 0.35
GPR3 P46089 1/20 0.34
NPC1 O15118 6/20 0.34
LMNA P02545 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15725992 0.86 ALDH1A1 (0.44) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL11992362 0.85 ALDH1A1 (0.53) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL12433611 0.85 CYP2A6 (0.40) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL12433600 0.83 ALDH1A1 (0.49) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL24614405 0.80 ALDH1A1 (0.42) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL18810716 0.79 ALDH1A1 (0.41) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL13562145 0.79 HPRT1 (0.44) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL26848020 0.79 MAPT (0.45) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL30743077 0.78 BCL2L1 (0.41) MAPTMEN1KMT2AALDH1A1GAA
SCHEMBL26293045 0.78 BCL2L1 (0.41) MAPTMEN1KMT2AALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2732479-B1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2019-09-11 EP disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-9583717-B2 Compounds for organic electroluminescent devices MERCK PATENT GMBH (DE) 2017-02-28 US disclosed
US-9190622-B2 Hybrid ambipolar TFTs MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-9190622-B2 Hybrid ambipolar TFTs MERCK PATENT GMBH (DE) 2015-11-17 US disclosed
US-9178159-B2 Copolymers with functionalized side chains MERCK PATENT GMBH (DE) 2015-11-03 US disclosed
US-20140175420-A1 COPOLYMERS WITH FUNCTIONALIZED SIDE CHAINS MERCK PATENT GMBH (DE) 2014-06-26 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
US-20140138661-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2014-05-22 US disclosed
WO-2013007348-A1 COMPOSITIONS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2013-01-17 WO disclosed
WO-2012163464-A1 HYBRID AMBIPOLAR TFTS MERCK PATENT GMBH (DE) 2012-12-06 WO disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100207516-A1 POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-08-19 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed