SCHEMBL12433669

SCHEMBL12433669

Cc1ccc2c(c1)N(c1ccccc1)c1cc(C)ccc1O2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
LMNA P02545 3/20 0.39
GAA P10253 2/20 0.39
TP53 P04637 1/20 0.39
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
HTT P42858 1/20 0.39
HKDC1 Q2TB90 1/20 0.39
P2RX4 Q99571 1/20 0.39
KDM4E B2RXH2 3/20 0.39
HSD17B10 Q99714 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
FGFR1 P11362 1/20 0.37
MIF P14174 2/20 0.36
CD74 P04233 1/20 0.36
MAOB P27338 1/20 0.35
MAPT P10636 1/20 0.35
HSP90AA1 P07900 1/20 0.34
MGLL Q99685 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11978697 0.95 P2RX4 (0.43) ALDH1A1LMNAGAATP53TSHR
SCHEMBL23606171 0.87 P2RX4 (0.35) ALDH1A1LMNAGAATP53TSHR
SCHEMBL16773717 0.86 P2RX4 (0.39) ALDH1A1P2RX4KDM4EHSD17B10SMN1; SMN2
SCHEMBL20172085 0.85 MAPT (0.36) ALDH1A1LMNAGAATP53TSHR
SCHEMBL12374349 0.85 ALDH1A1 (0.42) ALDH1A1LMNAGAATP53TSHR
SCHEMBL13203012 0.84 P2RX4 (0.43) ALDH1A1LMNAP2RX4KDM4EHSD17B10
SCHEMBL27967977 0.82 AGTR1 (0.43) MAPK1P2RX4
SCHEMBL1611442 0.80 ALDH1A1 (0.42) ALDH1A1LMNAGAATP53TSHR
SCHEMBL1612154 0.80 ALDH1A1 (0.42) ALDH1A1LMNAGAATP53TSHR
SCHEMBL16327690 0.79 ALDH1A1 (0.36) ALDH1A1LMNAGAATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-7982212-B2 Copolymer and polymer light emitting device using the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-19 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed
US-20100176376-A1 COPOLYMER AND POLYMER LIGHT EMITTING DEVICE USING THE SAME SUMITOMO CHEMICAL COMPANY , LIMITED (JP) 2010-07-15 US disclosed