SCHEMBL12433870

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11808662	0.90	CHRM2 (0.46)	CHRM2UTS2RSMN1; SMN2HTR1AADRA1D
	SCHEMBL6173269	0.84	CHRM2 (0.70)	CHRM2UTS2RGBA1SMN1; SMN2HTR1A
	SCHEMBL14226176	0.83	MAPT (0.44)	CHRM2UTS2RGBA1SMN1; SMN2HTR1A
	SCHEMBL9132120	0.82	SMN1; SMN2 (0.47)	CHRM2SMN1; SMN2TSHRALDH1A1GAA
	SCHEMBL27982786	0.81	TSHR (0.55)	CHRM2GBA1SMN1; SMN2HTR1AADRA1D
	SCHEMBL11496106	0.79	CHRM2 (0.73)	CHRM2UTS2RGBA1SMN1; SMN2HTR1A
	SCHEMBL24277324	0.79	CHRM2 (0.48)	CHRM2SMN1; SMN2HTR1AADRA1DADRA1A
	SCHEMBL24277459	0.79	CHRM2 (0.48)	CHRM2SMN1; SMN2HTR1AADRA1DADRA1A
	SCHEMBL27973788	0.78	NR3C1 (0.42)	UTS2RGBA1SMN1; SMN2TSHRALDH1A1
	SCHEMBL6933746	0.78	CHRM2 (0.76)	CHRM2GBA1SMN1; SMN2HTR1AADRA1D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.