Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 9/20 | 0.76 |
| ▸ | GBA1 | P04062 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.46 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.46 |
| ▸ | BCHE | P06276 | 4/20 | 0.46 |
| ▸ | ACHE | P22303 | 4/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5287093 | 1.00 | CHRM2 (0.76) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL10490579 | 1.00 | CHRM2 (0.76) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL11634725 | 1.00 | CHRM2 (0.76) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL11496106 | 0.98 | CHRM2 (0.73) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL6173269 | 0.93 | CHRM2 (0.70) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL23467818 | 0.88 | CHRM2 (0.97) | CHRM2GRIN1GRIN2ABCHEACHE | |
| SCHEMBL22652639 | 0.88 | CHRM2 (0.97) | CHRM2GRIN1GRIN2ABCHEACHE | |
| SCHEMBL16139561 | 0.88 | CHRM2 (0.97) | CHRM2GRIN1GRIN2ABCHEACHE | |
| SCHEMBL1644001 | 0.85 | CHRM2 (0.64) | CHRM2GBA1HTR1AADRA1DADRA1A | |
| SCHEMBL2397251 | 0.85 | CHRM2 (0.56) | CHRM2GBA1HTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6610805-B1 | Ligands having a backbone comprised of amine-C-C-X where X is alkoxy or alkylsulfide, for example: 2-(Octylamino)anisole; coordinated with a transition metal and ligand | SYMYX TECHNOLOGIES, INC. | 2003-08-26 | — | — | US | disclosed |
| US-6534664-B1 | Polymerization catalysts | SYMYX TECHNOLOGIES, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6521793-B1 | Aromatic secondary amines; polymerization catalysts | SYMYX TECHNOLOGIES, INC. | 2003-02-18 | — | — | US | disclosed |
| US-20020072632-A1 | Catalyst ligands, catalytic metal complexes and processes using same | SYMYX TECHNOLOGIES | 2002-06-13 | — | — | US | disclosed |
| EP-1037872-A1 | CATALYST LIGANDS, CATALYTIC METAL COMPLEXES AND PROCESSES USING SAME | SYMYX TECHNOLOGIES (US) | 2000-09-27 | — | — | EP | disclosed |
| WO-2000020377-A1 | CATALYST LIGANDS, CATALYTIC METAL COMPLEXES AND PROCESSES USING SAME | SYMYX TECHNOLOGIES (US) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000008032-A1 | CATALYST LIGANDS USEFUL FOR CROSS-COUPLING REACTIONS | SYMYX TECHNOLOGIES, INC. (US) | 2000-02-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072632-A1 | Catalyst ligands, catalytic metal complexes and processes using same | CLPX, PICALM, SOD1 | CHRM2 4017/4885GBA1 288/4885HTR1A 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.