SCHEMBL12433901

SCHEMBL12433901

Cc1ccc(COc2ccc(N(c3ccccc3)c3ccc(/C=N/N(c4ccccc4)c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
CASP3 P42574 2/20 0.55
SENP8 Q96LD8 2/20 0.55
SENP7 Q9BQF6 2/20 0.55
SENP6 Q9GZR1 2/20 0.55
ALDH1A1 P00352 3/20 0.45
KDM4E B2RXH2 2/20 0.45
AMY1A P0DUB6 1/20 0.45
TSHR P16473 1/20 0.45
NR1H4 Q96RI1 1/20 0.44
KMT2A Q03164 5/20 0.43
MEN1 O00255 4/20 0.43
MAPT P10636 3/20 0.43
LMNA P02545 1/20 0.43
GAA P10253 1/20 0.43
THRB P10828 1/20 0.43
PKM P14618 1/20 0.43
RECQL P46063 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14087532 1.00 NPC1 (0.55) NPC1RAB9ASMN1; SMN2CASP3SENP8
SCHEMBL8150622 0.84 MAOB (0.51) NPC1RAB9ASMN1; SMN2CASP3SENP8
SCHEMBL359917 0.84 MEN1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL12677649 0.84 MEN1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL1199116 0.84 MEN1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL1199348 0.84 MEN1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL1199117 0.84 MEN1 (0.48) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL13986164 0.84 LMNA (0.43) NPC1RAB9ASMN1; SMN2CASP3SENP8
SCHEMBL17366374 0.83 GAA (0.52) NPC1RAB9ASMN1; SMN2ALDH1A1KDM4E
SCHEMBL13777672 0.82 SMN1; SMN2 (0.40) NPC1RAB9ASMN1; SMN2CASP3SENP8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2019338-B1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEM CORP (JP) 2013-07-03 EP disclosed
US-8404411-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 US disclosed
US-8404411-B2 Electrophotographic photoreceptor, image-forming apparatus, and electrophotographic cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2013-03-26 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-8273509-B2 Electrophotographic photoreceptor, and image forming device and electrophotographic photoreceptor cartridge using the same member cartridge MITSUBISHI CHEMICAL CORPORATION (JP) 2012-09-25 US disclosed
US-7981581-B2 Halogenated phthalocyanine compounds; high sensitivity, small environmental dependence, only small fluctuations in electrical properties when the usage environment varies during repeated use MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-7981581-B2 Halogenated phthalocyanine compounds; high sensitivity, small environmental dependence, only small fluctuations in electrical properties when the usage environment varies during repeated use MITSUBISHI CHEMICAL CORPORATION (JP) 2011-07-19 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090232551-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, IMAGE FORMING DEVICE USING SAME, AND ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-09-17 US disclosed
US-20090208250-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-20 US disclosed
US-20090208250-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, IMAGE-FORMING APPARATUS, AND ELECTROPHOTOGRAPHIC CARTRIDGE MITSUBISHI CHEMICAL CORPORATION (JP) 2009-08-20 US disclosed
EP-2019338-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE FORMING DEVICE, AND ELECTROPHOTOGRAPHIC CARTRIDGE Mitsubishi Chemical Corporation (JP) 2009-01-28 EP disclosed
US-20080268357-A1 Phthalocyanine Composition and Photoconductive Material, Electrophotographic Photoreceptor Cartridge, and Image-Forming Apparatus Each Employing the Composition MITSUBISHI CHEMICAL CORPORATION (JP) 2008-10-30 US disclosed
US-20080268357-A1 Phthalocyanine Composition and Photoconductive Material, Electrophotographic Photoreceptor Cartridge, and Image-Forming Apparatus Each Employing the Composition MITSUBISHI CHEMICAL CORPORATION (JP) 2008-10-30 US disclosed