SCHEMBL1199348

SCHEMBL1199348

Cc1ccc(N(c2ccc(C)cc2)c2ccc(/C=N/N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.48
KMT2A Q03164 7/20 0.48
CYP1A2 P05177 1/20 0.47
CYP3A4 P08684 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
ALDH1A1 P00352 4/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
MAPT P10636 3/20 0.46
MAPK1 P28482 3/20 0.46
LMNA P02545 1/20 0.46
GAA P10253 2/20 0.43
HTT P42858 1/20 0.43
MCL1 Q07820 1/20 0.43
USP2 O75604 2/20 0.42
NPC1 O15118 1/20 0.42
RAB9A P51151 1/20 0.42
G6PC1 P35575 1/20 0.42
POLB P06746 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12677649 1.00 MEN1 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL1199116 1.00 MEN1 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL359917 1.00 MEN1 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL1199117 1.00 MEN1 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL12083950 0.95 MEN1 (0.45) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL15292551 0.93 SMN1; SMN2 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL12677636 0.93 SMN1; SMN2 (0.48) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL15600374 0.93 CYP2A6 (0.46) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL15600309 0.93 CYP2A6 (0.46) MEN1KMT2ACYP1A2CYP3A4CYP2D6
SCHEMBL15600206 0.93 CYP2A6 (0.46) MEN1KMT2ACYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7884245-B2 reacting a diphenylamine with acetic acid and sodium nitrite to obatain a N-nitrosoamine compound, adding thiourea dioxide and NaOH to such reaction solution to reduce nitrosoamine compound to a hydrazine compound, condensing hydrazins with p-diphenylaminobenzaldehyde to form end product hydrazones HODOGAYA CHEMICAL CO., LTD. (JP) 2011-02-08 US claimed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20230273535-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING DEVICE MITSUBISHI CHEMICAL CORPORATION (JP) 2023-08-31 US disclosed
US-20220197162-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE AND IMAGE FORMING APPARATUS MITSUBISHI CHEMICAL CORPORATION (JP) 2022-06-23 US disclosed
EP-3438752-B1 POSITIVELY CHARGEABLE ELECTROPHOTOGRAPHIC PHOTORECEPTOR, ELECTROPHOTOGRAPHIC PHOTORECEPTOR CARTRIDGE, AND IMAGE FORMING APPARATUS MITSUBISHI CHEM CORP (JP) 2022-01-12 EP disclosed
US-11188002-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2021-11-30 US disclosed
US-11181838-B2 Electrophotographic photoreceptor, electrophotographic photoreceptor cartridge and image forming apparatus MITSUBISHI CHEMICAL CORPORATION (JP) 2021-11-23 US disclosed
US-10884348-B2 Electrophotographic photoreceptor, and electrophotographic cartridge and image forming apparatus including same MITSUBISHI CHEMICAL CORPORATION (JP) 2021-01-05 US disclosed
US-10802411-B2 Electrophotographic photosensitive member, process cartridge, and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2020-10-13 US disclosed
US-10790430-B2 Thermoelectric conversion element and thermoelectric conversion power generation device NAKAYA HIROAKI (JP) 2020-09-29 US disclosed
US-20080268357-A1 Phthalocyanine Composition and Photoconductive Material, Electrophotographic Photoreceptor Cartridge, and Image-Forming Apparatus Each Employing the Composition MITSUBISHI CHEMICAL CORPORATION (JP) 2008-10-30 US disclosed
EP-1930778-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE BODY, IMAGE-FORMING DEVICE USING SAME AND CARTRIDGE Mitsubishi Chemical Corporation (JP) 2008-06-11 EP disclosed
US-20080026310-A1 Oxo-titanylphthalocyanine crystal, method for producing the same, and electrophotographic photoreceptor TAE TECHNOLOGIES 2008-01-31 US disclosed
US-20080026310-A1 Oxo-titanylphthalocyanine crystal, method for producing the same, and electrophotographic photoreceptor TAE TECHNOLOGIES 2008-01-31 US disclosed
US-20080015387-A1 Process for Producing Hydrazone Compound HODOGAYA CHEMICAL CO., LTD. (JP) 2008-01-17 US disclosed
US-20070281227-A1 Multilayer type electrophotographic photoconductor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2007-12-06 US disclosed
US-20070281227-A1 Multilayer type electrophotographic photoconductor and image forming apparatus KYOCERA DOCUMENT SOLUTIONS INC. (JP) 2007-12-06 US disclosed
US-20070217821-A1 Image forming apparatus KYOCERA MITA CORPORATION (JP) 2007-09-20 US disclosed
US-20070217821-A1 Image forming apparatus KYOCERA MITA CORPORATION (JP) 2007-09-20 US disclosed
EP-1762564-A1 PROCESS FOR PRODUCING HYDRAZONE COMPOUND Hodogaya Chemical Co., Ltd. (JP) 2007-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080026310-A1 Oxo-titanylphthalocyanine crystal, method for producing the same, and electrophotographic photoreceptor ALDH1A2, ADH1C, ADH1A MEN1 3947/4885KMT2A 3717/4885CYP1A2 1565/4885
US-20080015387-A1 Process for Producing Hydrazone Compound KEAP1, FH, CYP3A5 MEN1 1041/4885KMT2A 1748/4885CYP1A2 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.