SCHEMBL12433903

SCHEMBL12433903

c1ccc(N(c2ccccc2)c2ccc(-c3ccc(-c4ccc5ccc6c(-c7ccc(N(c8ccccc8)c8ccccc8)cc7)ccc7ccc4c5c76)cc3)cc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.39
CYP1A2 P05177 3/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
TDP1 Q9NUW8 2/20 0.39
KDM4E B2RXH2 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
MAPT P10636 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
CRHBP P24387 1/20 0.34
ATM Q13315 1/20 0.34
CRHR2 Q13324 1/20 0.34
TLR9 Q9NR96 1/20 0.34
APP P05067 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2208571 0.98 ALDH1A1 (0.38) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL10029021 0.98 ALDH1A1 (0.41) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL9921115 0.96 ALDH1A1 (0.39) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL18174845 0.94 CYP1A2 (0.39) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL18174848 0.93 CYP1A2 (0.41) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL17263972 0.92 ALDH1A1 (0.34) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL18416119 0.92 CYP1A2 (0.38) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL18174838 0.92 CYP1A2 (0.40) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL17263968 0.91 KDM4E (0.33) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E
SCHEMBL17562214 0.90 ALDH1A1 (0.35) ALDH1A1CYP1A2L3MBTL1TDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7981523-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-07-19 US disclosed
US-7981523-B2 Aromatic amine derivative and organic electroluminescence device using the same IDEMITSU KOSAN CO., LTD. (JP) 2011-07-19 US disclosed