SCHEMBL18174838

SCHEMBL18174838

c1ccc(-c2ccc(N(c3ccc(-c4ccccc4)cc3)c3ccc(-c4ccc5ccc6cccc7ccc4c5c67)cc3)cc2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.40
ERBB2 P04626 1/20 0.40
FYN P06241 1/20 0.40
MAOA P21397 1/20 0.40
ACHE P22303 1/20 0.40
AHR P35869 1/20 0.40
ALDH1A1 P00352 7/20 0.38
HSD17B10 Q99714 5/20 0.38
HPGD P15428 5/20 0.38
THRB P10828 1/20 0.38
CYP3A4 P08684 3/20 0.38
TSHR P16473 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
TNF P01375 1/20 0.36
HSD17B1 P14061 1/20 0.36
HSD17B2 P37059 1/20 0.36
CYP1A1 P04798 1/20 0.35
CYP1B1 Q16678 1/20 0.35
PDE6D O43924 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18174845 0.98 CYP1A2 (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL18174848 0.95 CYP1A2 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL2208571 0.93 ALDH1A1 (0.38) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL10025665 0.93 ALDH1A1 (0.42) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL29395264 0.93 ALDH1A1 (0.42) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL12433903 0.92 ALDH1A1 (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL9921115 0.92 ALDH1A1 (0.39) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL10029021 0.90 ALDH1A1 (0.41) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL6387948 0.90 CYP1A2 (0.47) CYP1A2ERBB2FYNMAOAACHE
SCHEMBL16639340 0.90 CYP1A2 (0.35) CYP1A2ERBB2FYNMAOAACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed
US-9478752-B2 Organic light-emitting diode comprising amine-based compounds and pyrene-based compounds SAMSUNG DISPLAY CO., LTD. (KR) 2016-10-25 US disclosed