Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MPI | P34949 | 1/20 | 0.34 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17263975 | 0.87 | KDM4E (0.33) | CYP1A2ALDH1A1MAPTKDM4EL3MBTL1 | |
| SCHEMBL22671106 | 0.86 | GPR84 (0.43) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL13758038 | 0.85 | MEN1 (0.40) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL12433908 | 0.85 | MAPT (0.37) | CYP1A2CYP2A6ALDH1A1MEN1MAPT | |
| SCHEMBL804834 | 0.83 | CYP11B1 (0.44) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL23472039 | 0.82 | GPR84 (0.44) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22671005 | 0.82 | MEN1 (0.40) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL22669945 | 0.82 | GPR84 (0.44) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL24221728 | 0.82 | CYP11B1 (0.42) | GPR84ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL185349 | 0.82 | TRPM4 (0.38) | GPR84CYP1A2CYP2A6ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7981523-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |
| US-7981523-B2 | Aromatic amine derivative and organic electroluminescence device using the same | IDEMITSU KOSAN CO., LTD. (JP) | 2011-07-19 | — | — | US | disclosed |