SCHEMBL185349

SCHEMBL185349

c1ccc(N(c2ccc(-c3ccc(N(c4ccccc4)c4cc5ccccc5c5ccccc45)cc3)cc2)c2cc3ccccc3c3ccccc23)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPM4 Q8TD43 1/20 0.38
ALDH1A1 P00352 6/20 0.38
HSD17B10 Q99714 3/20 0.38
HIF1A Q16665 2/20 0.38
CYP1B1 Q16678 1/20 0.38
GPR84 Q9NQS5 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HPRT1 P00492 1/20 0.35
MAPT P10636 4/20 0.35
KDM4E B2RXH2 4/20 0.35
CYP1A2 P05177 3/20 0.35
CYP2C19 P33261 3/20 0.35
TDP1 Q9NUW8 2/20 0.35
CYP3A4 P08684 2/20 0.35
CYP2D6 P10635 2/20 0.35
CYP2C9 P11712 2/20 0.35
APAF1 O14727 1/20 0.35
CASP3 P42574 1/20 0.35
CASP6 P55212 1/20 0.35
SENP8 Q96LD8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16305470 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL29462253 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL29776694 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL29776839 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL18069084 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL16158275 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13658667 1.00 TRPM4 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL13854564 0.98 ALDH1A1 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL22671921 0.98 GPR84 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1
SCHEMBL16158232 0.98 GPR84 (0.38) TRPM4ALDH1A1HSD17B10HIF1ACYP1B1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1246 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260082802-A1 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR PRODUCING AN ORGANIC ELECTRONIC COMPONENT PICTIVA DISPLAYS INTERNATIONAL LIMITED (IE) 2026-03-19 US claimed
EP-4557929-A2 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS CREDOXYS GmbH (DE) 2025-05-21 EP claimed
EP-4029069-B1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2025-04-09 EP claimed
EP-4244910-B1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2024-12-11 EP claimed
US-20240247004-A1 NEW CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2024-07-25 US claimed
EP-4305681-A1 NEW CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS CREDOXYS GmbH (DE) 2024-01-17 EP claimed
US-20230422602-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2023-12-28 US claimed
US-11849598-B2 Organic light-emitting component having a light-emitting layer as part of a charge generation layer PICTIVA DISPLAYS INTERNATIONAL LIMITED (IE) 2023-12-19 US claimed
US-20230092935-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2023-03-23 US claimed
WO-2022189431-A1 NEW CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS Credoxys GmbH (DE) 2022-09-15 WO claimed
US-20120146006-A1 MATERIAL FOR A HOLE TRANSPORT LAYER WITH P-DOPANT NOVALED GMBH (DE) 2012-06-14 US claimed
US-20120003485-A1 Monolayers of organic compounds on metal oxide surfaces or metal surfaces containing oxide and component produced therewith based on organic electronics SIEMENS AKTIENGESELLSCHAFT (DE) 2012-01-05 US claimed
US-8057712-B2 Radialene compounds and their use NOVALED AG (DE) 2011-11-15 US claimed
EP-2180029-B1 Radialene compounds and their use NOVALED AG (DE) 2011-07-27 EP claimed
US-20100102709-A1 RADIALENE COMPOUNDS AND THEIR USE NOVALED AG (DE) 2010-04-29 US claimed
EP-2180029-A1 Radialene compounds and their use Novaled AG (DE) 2010-04-28 EP claimed
US-20060255322-A1 Methods and compositions for improved electrophoretic display performance WU ZARNG-ARH G 2006-11-16 US claimed
EP-1529242-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER Sipix Imaging, Inc. (US) 2005-05-11 EP claimed
US-20040085619-A1 Novel Methods and compositions for improved electrophoretic display performance SIPIX IMAGING, INC. 2004-05-06 US claimed
WO-2004010206-A2 PROTECTING LAYER WITH ADDITIVES FOR ELECTROPHORETIC DISPLAY, METHOD OF PROVIDING SUCH LAYER, AND ELECTROPHORETIC DISPLAY WITH SUCH A LAYER SIPIX IMAGING, INC. (US) 2004-01-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100102709-A1 RADIALENE COMPOUNDS AND THEIR USE CHRNB2, CHRNB3, CHRNB4 TRPM4 415/4885ALDH1A1 3374/4885HSD17B10 1478/4885
US-20240247004-A1 NEW CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS PIN4, CPNE4, CLN6 TRPM4 143/4885ALDH1A1 3926/4885HSD17B10 4545/4885
US-20260082802-A1 ORGANIC ELECTRONIC COMPONENT AND METHOD FOR PRODUCING AN ORGANIC ELECTRONIC COMPONENT FLNA, FLNB, CDH1 TRPM4 385/4885ALDH1A1 949/4885HSD17B10 3930/4885
US-20230092935-A1 CERIUM (IV) COMPLEXES AND THEIR USE IN ORGANIC ELECTRONICS CLIC4, KCNN4, CLN6 TRPM4 126/4885ALDH1A1 4171/4885HSD17B10 3893/4885
US-20230422602-A1 CERIUM-ETHYLENEDIAMINE KETONE-TYPE AND CERIUM-SALEN-TYPE COMPLEXES AND USE THEREOF IN ORGANIC ELECTRONICS KCNH3, KCNE1, PDHA1 TRPM4 1080/4885ALDH1A1 1811/4885HSD17B10 3670/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.