Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARD | Q03181 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL202251 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL14421930 | 0.89 | ALDH1A1 (0.50) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL204177 | 0.86 | ALDH1A1 (0.55) | ALDH1A1TDP1L3MBTL1KMT2AMEN1 | |
| SCHEMBL203502 | 0.86 | ALDH1A1 (0.37) | ALDH1A1TDP1L3MBTL1KMT2AFFAR1 | |
| SCHEMBL19471079 | 0.79 | HRH3 (0.41) | KMT2AFFAR1PPARGPPARDMEN1 | |
| SCHEMBL17274943 | 0.79 | HRH3 (0.41) | KMT2AFFAR1PPARGPPARDMEN1 | |
| SCHEMBL201929 | 0.78 | MEN1 (0.44) | ALDH1A1KMT2AMEN1TNKS2MAPT | |
| SCHEMBL17274940 | 0.77 | CYP1A2 (0.42) | ALDH1A1KMT2AFFAR1PPARGPPARD | |
| SCHEMBL203389 | 0.77 | MEN1 (0.54) | ALDH1A1KMT2AMEN1MAPTCYP3A4 | |
| SCHEMBL202528 | 0.77 | MEN1 (0.54) | ALDH1A1KMT2AMEN1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |
| WO-2007107758-A1 | ANTIBACTERIAL AGENTS | PROLYSIS LTD (GB) | 2007-09-27 | — | — | WO | disclosed |