SCHEMBL204177

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL202251	0.95	ALDH1A1 (0.50)	ALDH1A1TDP1L3MBTL1KMT2ANPC1
	SCHEMBL14421930	0.95	ALDH1A1 (0.50)	ALDH1A1TDP1L3MBTL1KMT2ANPC1
	SCHEMBL203187	0.89	MEN1 (0.43)	ALDH1A1TDP1L3MBTL1KMT2ANPC1
	SCHEMBL12434183	0.86	ALDH1A1 (0.43)	ALDH1A1TDP1L3MBTL1KMT2AMAPK1
	SCHEMBL202528	0.83	MEN1 (0.54)	ALDH1A1KMT2AMEN1NR1I2LMNA
	SCHEMBL203389	0.83	MEN1 (0.54)	ALDH1A1KMT2AMEN1NR1I2LMNA
	SCHEMBL203502	0.82	ALDH1A1 (0.37)	ALDH1A1TDP1L3MBTL1KMT2ATNKS2
	SCHEMBL201929	0.81	MEN1 (0.44)	ALDH1A1KMT2ATNKS2KDM4EMEN1
	SCHEMBL17712588	0.81	MAPT (0.46)	ALDH1A1KMT2ASMN1; SMN2TNKS2KDM4E
	SCHEMBL200889	0.80	ATM (0.41)	ALDH1A1TDP1L3MBTL1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.