Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.61 |
| ▸ | NPC1 | O15118 | 8/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | PKM | P14618 | 2/20 | 0.57 |
| ▸ | ATM | Q13315 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4439807 | 0.83 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL1486703 | 0.83 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL202064 | 0.83 | RAB9A (0.61) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL8888284 | 0.83 | MCL1 (0.65) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL4442344 | 0.81 | MCL1 (0.66) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL14946436 | 0.79 | RAB9A (0.64) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL4440742 | 0.78 | MCL1 (0.63) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL4440934 | 0.77 | HDAC1 (0.62) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL6325635 | 0.76 | MCL1 (1.00) | RAB9ANPC1SMN1; SMN2MAPTMCL1 | |
| SCHEMBL19287090 | 0.75 | MCL1 (0.62) | RAB9ANPC1SMN1; SMN2MAPTMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1996180-B1 | BENZAMIDE AND PYRIDYLAMIDE DERIVATIVES AS ANTIBACTERIAL AGENTS | BIOTA EUROPE LTD (GB) | 2011-08-03 | — | — | EP | disclosed |