Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.61 |
| ▸ | RAB9A | P51151 | 5/20 | 0.60 |
| ▸ | NPC1 | O15118 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4440742 | 0.96 | MCL1 (0.63) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL4442344 | 0.90 | MCL1 (0.66) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL4439807 | 0.83 | RAB9A (0.61) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL19287090 | 0.81 | MCL1 (0.62) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL2031451 | 0.78 | HDAC1 (0.67) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL2028282 | 0.77 | HDAC1 (0.69) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL12434381 | 0.77 | RAB9A (0.61) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL1486703 | 0.77 | RAB9A (0.61) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL8888284 | 0.77 | MCL1 (0.65) | HDAC1HDAC2HDAC8MCL1RAB9A | |
| SCHEMBL202064 | 0.77 | RAB9A (0.61) | HDAC1HDAC2HDAC8MCL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2044064-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2009-04-08 | — | — | EP | claimed |
| WO-2008003861-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2008-01-10 | — | — | WO | claimed |
| EP-2044064-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2009-04-08 | — | — | EP | disclosed |
| WO-2008003861-A1 | COMPOUNDS HAVING A POTENTIATING EFFECT ON THE ACTIVITY OF ETHIONAMIDE AND USES THEREOF | INSTITUT PASTEUR DE LILLE (FR) | 2008-01-10 | — | — | WO | disclosed |