Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 4/20 | 0.40 |
| ▸ | FAAH | O00519 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12434582 | 0.83 | HDAC3 (0.40) | SMN1; SMN2HDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL12434577 | 0.80 | EPHX2 (0.49) | EPHX2FAAHMEN1KMT2AASAH1 | |
| SCHEMBL17368565 | 0.78 | FAAH (0.51) | EPHX2FAAHMEN1KMT2AASAH1 | |
| Bromide SCHEMBL29172337 | 0.73 | — | — | |
| SCHEMBL13306017 | 0.70 | KDM4E (0.38) | EPHX2GAASMN1; SMN2HPGDTSHR | |
| SCHEMBL23480805 | 0.69 | EPHX2 (0.50) | EPHX2MEN1KMT2AASAH1SMN1; SMN2 | |
| SCHEMBL9858723 | 0.67 | HPGD (0.61) | EPHX2HPGD | |
| SCHEMBL10925762 | 0.66 | HDAC1 (0.68) | EPHX2MEN1KMT2AHPGDTSHR | |
| SCHEMBL28764825 | 0.66 | HDAC1 (0.68) | EPHX2MEN1KMT2AHPGDTSHR | |
| SCHEMBL13626338 | 0.66 | HDAC1 (0.68) | EPHX2MEN1KMT2AHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8772544-B2 | Process for the production of bimatoprost | SANDOZ AG (CH) | 2014-07-08 | — | — | US | disclosed |
| US-20110178340-A1 | IMPROVED PROCESS FOR THE PRODUCTION OF BIMATOPROST | SANDOZ AG (CH) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178340-A1 | IMPROVED PROCESS FOR THE PRODUCTION OF BIMATOPROST | AVPR2, PTGIR, ADH1A | EPHX2 1997/4885FAAH 187/4885MEN1 4110/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.