Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.55 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14975419 | 1.00 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL14975416 | 1.00 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL12435125 | 1.00 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL15329138 | 1.00 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL11855651 | 0.82 | SLC7A5 (0.46) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL18211555 | 0.79 | ALDH1A1 (0.37) | SLC7A5PTGS1ALDH1A1MAPT | |
| SCHEMBL3891579 | 0.79 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| SCHEMBL4441664 | 0.79 | SLC7A5 (0.55) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| Methane SCHEMBL2033946 | 0.77 | SLC7A5 (0.52) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 | |
| Methane SCHEMBL2032537 | 0.77 | SLC7A5 (0.52) | SLC7A5PTGS1ALDH1A1MAPTSLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2353714-A1 | ASYMMETRIC HYDROGENATION CATALYST | Takasago International Corporation (JP) | 2011-08-10 | — | — | EP | disclosed |