Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.30 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.30 |
| ▸ | ELANE | P08246 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12401267 | 0.93 | TGM2 (0.32) | TGM2ITGB3ITGA2BELANE | |
| SCHEMBL12401268 | 0.92 | TGM2 (0.32) | TGM2ELANE | |
| SCHEMBL12401271 | 0.89 | TGM2 (0.32) | TGM2ELANE | |
| SCHEMBL12401287 | 0.87 | ITGB3 (0.32) | TGM2ITGB3ITGA2BELANE | |
| SCHEMBL12401281 | 0.86 | TGM2 (0.33) | TGM2ITGB3ITGA2BELANE | |
| SCHEMBL12401283 | 0.84 | TGM2 (0.33) | TGM2ITGB3ITGA2BELANE | |
| SCHEMBL12401326 | 0.81 | CYP3A4 (0.32) | — | |
| SCHEMBL12401323 | 0.80 | CYP3A4 (0.33) | ELANE | |
| SCHEMBL12435229 | 0.80 | CYP3A4 (0.31) | — | |
| SCHEMBL15478237 | 0.80 | CYP3A4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011091757-A1 | POLYHETEROCYCLIC COMPOUNDS HIGHLY POTENT AS HCV INHIBITORS | AB Pharma Ltd. (CN) | 2011-08-04 | — | — | WO | disclosed |