Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.44 |
| ▸ | FDPS | P14324 | 17/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12048107 | 0.85 | FDPS (0.56) | GGPS1FDPS | |
| SCHEMBL12048156 | 0.79 | GGPS1 (0.47) | GGPS1FDPS | |
| SCHEMBL12060361 | 0.71 | FDPS (0.43) | GGPS1FDPS | |
| SCHEMBL12060628 | 0.69 | GGPS1 (0.62) | GGPS1FDPS | |
| SCHEMBL12060363 | 0.67 | FDPS (0.54) | GGPS1FDPS | |
| SCHEMBL12060352 | 0.66 | GGPS1 (0.84) | GGPS1FDPS | |
| SCHEMBL12048164 | 0.66 | GGPS1 (0.38) | GGPS1FDPS | |
| SCHEMBL12048185 | 0.65 | GGPS1 (0.57) | GGPS1FDPS | |
| SCHEMBL12060545 | 0.64 | GGPS1 (0.57) | GGPS1FDPS | |
| SCHEMBL12060353 | 0.64 | GGPS1 (0.52) | GGPS1FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802641-B1 | BISPHOSPHONATE COMPOUNDS AND METHODS FOR BONE RESORPTION DISEASES, CANCER, BONE PAIN, IMMUNE DISORDERS, AND INFECTIOUS DISEASES | UNIV ILLINOIS (US) | 2011-08-10 | — | — | EP | disclosed |