Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.57 |
| ▸ | FDPS | P14324 | 9/20 | 0.44 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12060628 | 0.91 | GGPS1 (0.62) | GGPS1FDPSPTPN5PTPN1 | |
| SCHEMBL12048146 | 0.87 | GGPS1 (0.76) | GGPS1FDPSPTPN5 | |
| SCHEMBL12048193 | 0.85 | FDPS (0.46) | GGPS1FDPS | |
| SCHEMBL12048155 | 0.85 | FDPS (0.49) | GGPS1FDPSPTPN5 | |
| SCHEMBL12048156 | 0.84 | GGPS1 (0.47) | GGPS1FDPS | |
| SCHEMBL12048151 | 0.83 | GGPS1 (0.78) | GGPS1FDPSPTPN5PTPN1 | |
| SCHEMBL12048206 | 0.80 | GGPS1 (0.52) | GGPS1FDPSPTPN5PTPN1 | |
| SCHEMBL12048152 | 0.79 | GGPS1 (0.48) | GGPS1FDPS | |
| SCHEMBL12048182 | 0.79 | FDPS (0.42) | GGPS1FDPS | |
| SCHEMBL12048203 | 0.79 | FDPS (0.40) | GGPS1FDPSPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8071573-B2 | Bisphosphonate compounds and methods for bone resorption diseases, cancer, bone pain, immune disorders, and infectious diseases | THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, A BODY CORPORATE AND POLITIC OF THE STATE OF ILLINOIS (US) | 2011-12-06 | — | — | US | disclosed |