Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA7 | P43166 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15607878 | 0.76 | CA1 (0.50) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL18926178 | 0.76 | KDM4E (0.34) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL10267444 | 0.76 | CA1 (0.45) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL19303377 | 0.75 | — | — | |
| SCHEMBL1869617 | 0.75 | — | — | |
| SCHEMBL15607872 | 0.74 | CA1 (0.38) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL15607869 | 0.74 | HTT (0.38) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL6953092 | 0.73 | EPHX1 (0.53) | CA1CA2CA9 | |
| SCHEMBL15649660 | 0.70 | ALDH1A1 (0.42) | KDM4EUSP2ALDH1A1LMNAMMP9 | |
| SCHEMBL28854646 | 0.70 | KDM4E (0.37) | KDM4EUSP2ALDH1A1LMNAMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092128-A1 | SUBSTITUTED NAPHTHYRIDINES AND THEIR USE AS SYK KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |