SCHEMBL28854646

SCHEMBL28854646

CC(C)(C)C(N)COS(C)(=O)=O

nearest known ligand 0.37

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.37
USP2 O75604 1/20 0.37
ALDH1A1 P00352 1/20 0.37
LMNA P02545 1/20 0.37
MMP9 P14780 1/20 0.37
ALOX15 P16050 1/20 0.37
TSHR P16473 1/20 0.37
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA9 Q16790 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29989722 0.80 CA1 (0.32) CA1CA2CA9
Hydrochloric Acid SCHEMBL7708259 0.75 CA1 (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
Hydrochloric Acid SCHEMBL7708261 0.75 CA1 (0.33) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL1869617 0.73
SCHEMBL19303377 0.73
SCHEMBL10431030 0.71 CYP24A1 (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL12436241 0.70 KDM4E (0.39) KDM4EUSP2ALDH1A1LMNAMMP9
Hydrochloric Acid SCHEMBL7115162 0.69 CA1 (0.31) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4755954 0.69 ALDH1A1 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9
SCHEMBL4755958 0.69 ALDH1A1 (0.42) KDM4EUSP2ALDH1A1LMNAMMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105503862-B Inhibitors of influenza viruses replication 沃泰克斯药物股份有限公司 2018-02-02 CN disclosed