Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | ACACB | O00763 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.51 |
| ▸ | MMP8 | P22894 | 1/20 | 0.51 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10117998 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL10117995 | 1.00 | ALDH1A1 (0.58) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL8691251 | 0.86 | ACACB (0.68) | HPGDNPC1ACACB | |
| SCHEMBL8691248 | 0.86 | ACACB (0.68) | HPGDNPC1ACACB | |
| SCHEMBL8134776 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL9046891 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL8701763 | 0.83 | ALDH1A1 (0.54) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL15918786 | 0.82 | ACACB (0.55) | ALDH1A1HPGDHSD17B10KDM4ELMNA | |
| SCHEMBL23240945 | 0.82 | HSD17B10 (0.51) | ALDH1A1HPGDHSD17B10KMT2AMEN1 | |
| SCHEMBL12203593 | 0.82 | CTSK (0.62) | ALDH1A1HPGDHSD17B10KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109563509-B | Reduced size self-delivering nucleic acid compounds targeting long non-coding RNAs | 菲奥医药公司 | 2022-08-09 | — | — | CN | disclosed |
| EP-2400846-B1 | HEPATITIS C VIRUS INHIBITORS | ENANTA PHARM INC (US) | 2016-10-05 | — | — | EP | disclosed |
| WO-2013052369-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES | ENANTA PHARMACEUTICALS, INC. (US) | 2013-04-11 | — | — | WO | disclosed |
| WO-2011091532-A1 | HEPATITIS C INHIBITOR COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2011-08-04 | — | — | WO | disclosed |