SCHEMBL12436368

SCHEMBL12436368

COC(=O)NC1(C)CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15506875 0.90 NPSR1 (0.34)
SCHEMBL15506868 0.90 NPSR1 (0.39)
SCHEMBL10527013 0.88 NPSR1 (0.38)
SCHEMBL19641035 0.84 KDM4E (0.38)
SCHEMBL26741050 0.82 TSHR (0.33)
Methyl Carbamate SCHEMBL11664166 0.81 ALDH1A1 (0.37)
Carbamic Acid SCHEMBL28572811 0.81 ALDH1A1 (0.37)
SCHEMBL24858087 0.80
SCHEMBL10481775 0.78 TSHR (0.34)
SCHEMBL3076558 0.78 TSHR (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119451683-A Oligonucleotide compositions and methods thereof 艾米利克斯制药公司 2025-02-14 CN disclosed
CN-110105434-B Stapled and stitched polypeptides and uses thereof 哈佛大学的校长及成员们 2024-09-17 CN disclosed
CN-118059096-A Methods of treating CNS disorders 杭州高光制药有限公司 2024-05-24 CN disclosed
CN-116490180-B Methods of treating CNS disorders 杭州高光制药有限公司 2024-03-22 CN disclosed
CN-114615999-B Drug antibody conjugates 法马马有限公司 2024-03-08 CN disclosed
WO-2022135442-A1 CDK2 INHIBITOR AND PREPARATION METHOD THEREFOR 上海拓界生物医药科技有限公司 2022-06-30 WO disclosed
CN-114615999-A Drug antibody conjugates 法马马有限公司 2022-06-10 CN disclosed
CN-114585370-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2022-06-03 CN disclosed
CN-114502177-A Oligonucleotide compositions and methods of use thereof 波涛生命科学有限公司 2022-05-13 CN disclosed
CN-113748116-A Techniques useful for oligonucleotide preparation 波涛生命科学有限公司 2021-12-03 CN disclosed
CN-105307667-B Stapled and sutured polypeptides and uses thereof 哈佛大学的校长及成员们 2019-04-19 CN disclosed
US-9266864-B2 VEGFR3 inhibitors CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2016-02-23 US disclosed
US-9238644-B2 VEGFR3 inhibitors CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2016-01-19 US disclosed
US-20160009686-A1 VEGFR3 INHIBITORS CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2016-01-14 US disclosed
US-20150225377-A1 VEGFR3 INHIBITORS CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2015-08-13 US disclosed
US-20140080798-A1 VEGFR3 INHIBITORS CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2014-03-20 US disclosed
US-20140073620-A1 VEGFR3 INHIBITORS CANCER THERAPEUTICS CRC PTY LIMITED (AU) 2014-03-13 US disclosed
WO-2013163466-A1 INHIBITORS OF HEPATITIS C VIRUS PRESIDIO PHARMACEUTICALS, INC. (US) 2013-10-31 WO disclosed
CN-102365025-A Conjugate-based systems for controlled drug delivery SMARTCELLS INC 2012-02-29 CN disclosed
WO-2011091532-A1 HEPATITIS C INHIBITOR COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2011-08-04 WO disclosed