Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Carbamic Acid SCHEMBL28572811 | 0.92 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 | |
| SCHEMBL10527013 | 0.92 | NPSR1 (0.38) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 | |
| SCHEMBL15506868 | 0.90 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 | |
| SCHEMBL15506875 | 0.86 | NPSR1 (0.34) | NPSR1MAPTLMNA | |
| SCHEMBL12436368 | 0.81 | — | — | |
| SCHEMBL28110455 | 0.80 | ALDH1A1 (0.35) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 | |
| SCHEMBL11737698 | 0.77 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2NPSR1MAPTMEN1 | |
| SCHEMBL10527009 | 0.76 | HDAC3 (0.33) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 | |
| SCHEMBL11733763 | 0.74 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2NPSR1CYP3A4MEN1 | |
| SCHEMBL2480644 | 0.74 | NPSR1 (0.36) | ALDH1A1SMN1; SMN2NPSR1MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | claimed |
| US-4069240-A | GROUP 8 METAL CATALYST | UNIROYAL, INC. (US) | 1978-01-17 | — | — | US | disclosed |