Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 13/20 | 0.50 |
| ▸ | GRIN2D | O15399 | 11/20 | 0.50 |
| ▸ | GRIN3B | O60391 | 11/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 11/20 | 0.50 |
| ▸ | GRIN2A | Q12879 | 11/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 11/20 | 0.50 |
| ▸ | GRIN2C | Q14957 | 11/20 | 0.50 |
| ▸ | GRIN3A | Q8TCU5 | 11/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 1/20 | 0.49 |
| ▸ | HTR2B | P41595 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | EBP | Q15125 | 1/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9059539 | 0.82 | SIGMAR1 (0.66) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22989550 | 0.75 | ALDH1A1 (0.40) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16194338 | 0.71 | ALDH1A1 (0.40) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL26885007 | 0.71 | TP53 (0.53) | CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL13588236 | 0.71 | NPC1 (0.50) | SIGMAR1MEN1KMT2A | |
| SCHEMBL23735897 | 0.67 | HDAC1 (0.50) | PKMMEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL29353343 | 0.67 | ALDH1A1 (0.53) | MEN1TSHRKMT2ACYP1A2 | |
| SCHEMBL588459 | 0.67 | ALDH1A1 (0.53) | MEN1TSHRKMT2ACYP1A2 | |
| SCHEMBL22251520 | 0.66 | ALDH1A1 (0.55) | MEN1ALOX15TSHRKMT2ACYP1A2 | |
| SCHEMBL11881598 | 0.66 | SIGMAR1 (0.58) | SIGMAR1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1925658-B1 | Modified copolymer containing lubricating oil additive composition and method of making the same | CHEVRON ORONITE CO (US) | 2011-08-03 | — | — | EP | disclosed |