Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.68 |
| ▸ | RAB9A | P51151 | 3/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.58 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.50 |
| ▸ | CCR3 | P51677 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437532 | 0.99 | HRH3 (0.69) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437525 | 0.99 | HRH3 (0.69) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437341 | 0.94 | OPRM1 (0.61) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437334 | 0.93 | OPRM1 (0.61) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437596 | 0.93 | HRH3 (0.61) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437549 | 0.92 | HRH3 (0.61) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437514 | 0.91 | HRH3 (0.67) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437540 | 0.91 | HRH3 (0.60) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437553 | 0.90 | HRH3 (0.58) | HRH3RAB9AOPRM1OPRD1MEN1 | |
| SCHEMBL12437356 | 0.89 | MEN1 (0.64) | HRH3RAB9AMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | AVALON PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | AVALON PHARMACEUTICALS | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | HPGDS, HPGD, DPYD | HRH3 788/4885RAB9A 3232/4885OPRM1 2073/4885 |
| US-20090036429-A1 | Hydroxypiperidine Derivatives and Uses Thereof | HPGDS, HPGD, DPYD | HRH3 788/4885RAB9A 3232/4885OPRM1 2073/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.