Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.41 |
| ▸ | DGAT2 | Q96PD7 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | SLC5A7 | Q9GZV3 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12437608 | 0.90 | KMT2A (0.55) | KMT2AMEN1ALDH1A1RAB9AROCK2 | |
| SCHEMBL13925119 | 0.89 | KMT2A (0.49) | KMT2AMEN1ALDH1A1MAPK1KAT6A | |
| SCHEMBL12437481 | 0.87 | ROCK2 (0.48) | KMT2AMEN1ALDH1A1MAPK1KAT6A | |
| SCHEMBL12437391 | 0.85 | MEN1 (0.53) | KMT2AMEN1KAT6ARAB9ASLC5A7 | |
| SCHEMBL12437390 | 0.84 | MEN1 (0.51) | KMT2AMEN1KAT6ARAB9ASLC5A7 | |
| SCHEMBL12437499 | 0.83 | TP53 (0.54) | KMT2AMEN1ALDH1A1RAB9AROCK2 | |
| SCHEMBL13925138 | 0.82 | KMT2A (0.53) | KMT2AMEN1ALDH1A1RAB9ASLC5A7 | |
| SCHEMBL12437394 | 0.81 | MEN1 (0.51) | KMT2AMEN1ALDH1A1KAT6ARAB9A | |
| SCHEMBL12437395 | 0.81 | MEN1 (0.53) | KMT2AMEN1KAT6ARAB9ASLC5A7 | |
| SCHEMBL12437503 | 0.80 | MCHR1 (0.49) | KMT2AMEN1KAT6ARAB9ASLC5A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | AVALON PHARMACEUTICALS | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178066-A1 | Hydroxypiperidine derivatives and uses thereof | HPGDS, HPGD, DPYD | KMT2A 2446/4885MEN1 3974/4885ALDH1A1 591/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.