Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15856528 | 0.72 | — | — | |
| SCHEMBL15259064 | 0.69 | LMNA (0.48) | LMNACYP2C9 | |
| SCHEMBL880 | 0.68 | — | — | |
| SCHEMBL21910751 | 0.68 | — | — | |
| SCHEMBL22905077 | 0.68 | — | — | |
| SCHEMBL879 | 0.68 | — | — | |
| SCHEMBL1331223 | 0.68 | — | — | |
| SCHEMBL7703385 | 0.68 | LMNA (0.42) | LMNACYP2C9 | |
| Water SCHEMBL23042868 | 0.67 | LMNA (0.96) | LMNACYP2C9 | |
| Water SCHEMBL23042869 | 0.67 | LMNA (0.96) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178043-A1 | Inhibitors of the mevalonate pathway of streptococcus pneumoniae | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
| US-20110178043-A1 | Inhibitors of the mevalonate pathway of streptococcus pneumoniae | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178043-A1 | Inhibitors of the mevalonate pathway of streptococcus pneumoniae | FNTA, GGPS1, HMGCR | LMNA 2363/4885CYP2C9 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.