Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15943737 | 0.89 | LMNA (0.42) | LMNACYP2C9 | |
| SCHEMBL15259064 | 0.77 | LMNA (0.48) | LMNACYP2C9 | |
| SCHEMBL9652640 | 0.75 | LMNA (0.45) | LMNACYP2C9 | |
| SCHEMBL15617989 | 0.74 | LMNA (0.42) | LMNACYP2C9 | |
| SCHEMBL3054764 | 0.71 | ALDH1A1 (0.32) | LMNA | |
| SCHEMBL575938 | 0.69 | LMNA (0.31) | LMNACYP2C9 | |
| SCHEMBL732557 | 0.68 | NR1I2 (0.31) | — | |
| SCHEMBL6406435 | 0.68 | — | — | |
| SCHEMBL12438024 | 0.68 | LMNA (0.52) | LMNACYP2C9 | |
| SCHEMBL31384135 | 0.67 | LMNA (0.37) | LMNACYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1056716-B1 | CYCLOHEXANEDIOLE DERIVATIVES | BASILEA PHARMACEUTICA AG (CH) | 2002-12-11 | — | — | EP | disclosed |
| US-6184422-B1 | TREATMENT AND PREVENTION OF HYPERPROLIFERATIVE SKIN DISEASES; REVERSING CONDITIONS ASSOCIATED WITH PHOTODAMAGE; ANTITUMOR, -CARCINOGENIC AGENTS; PSORIASIS; DISORDERS OF NEOPLASTIC DISEASES; KERATINIZATION/KERATOSIS; ACNE; SEBORRHEA | HOFFMAN-LA ROCHE INC. | 2001-02-06 | — | — | US | disclosed |
| EP-1056716-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2000-12-06 | — | — | EP | disclosed |
| WO-1999043646-A1 | CYCLOHEXANEDIOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 1999-09-02 | — | — | WO | disclosed |