Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 1/20 | 0.73 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.69 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
| ▸ | PRKCA | P17252 | 1/20 | 0.69 |
| ▸ | MAPT | P10636 | 1/20 | 0.65 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.64 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.64 |
| ▸ | LPAR3 | Q9UBY5 | 4/20 | 0.64 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.64 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.64 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.64 |
| ▸ | CES2 | O00748 | 1/20 | 0.64 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.64 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | BLM | P54132 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | FAAH | O00519 | 2/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10655052 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL2396746 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9169289 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL9169298 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL10655057 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL3658169 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL2396742 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL332985 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| SCHEMBL332986 | 1.00 | DGKA (0.73) | DGKAPRKCEPRKCQPRKCDPRKCA | |
| Ammonia Solution, Strong SCHEMBL8661319 | 0.98 | DGKA (0.71) | DGKAPRKCEPRKCQPRKCDPRKCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9670200-B2 | Quaternary ammonium salt prodrugs | ALKERMES PHARMA IRELAND LIMITED (IE) | 2017-06-06 | — | — | US | disclosed |
| US-20110178068-A1 | Quaternary Ammonium Salt Prodrugs | ALKERMES, INC. (US) | 2011-07-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110178068-A1 | Quaternary Ammonium Salt Prodrugs | SLC1A5, IDH1, ASS1 | DGKA 4871/4885PRKCE 4746/4885PRKCQ 4276/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.