SCHEMBL1243854

SCHEMBL1243854

CC(N)C(CO)NCCO

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PAX8 Q06710 1/20 0.34
LMNA P02545 2/20 0.31
CNR1 P21554 1/20 0.31
ADRA1A P35348 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
KDM4E B2RXH2 1/20 0.31
SLC6A4 P31645 1/20 0.31
TSHR P16473 1/20 0.30
ABCC3 O15438 1/20 0.30
HSD17B10 Q99714 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2924806 0.80 TRPV3 (0.34) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL352466 0.77 LMNA (0.38) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL10889620 0.76 LMNA (0.31) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL19099867 0.75
SCHEMBL2713805 0.75
SCHEMBL730154 0.74 LMNA (0.39) LMNACNR1ADRA1ATDP1KDM4E
SCHEMBL26716230 0.74 TDP1 (0.33) PAX8LMNACNR1ADRA1ATDP1
SCHEMBL20762441 0.74
SCHEMBL27098 0.74
SCHEMBL2378324 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7960321-B2 Reaction product of a hydroxyaromatic compound, an aldehyde, an N-hydroxyethyl substituted diamine, and a molybdenum source AFTON CHEMICAL CORPORATION (US) 2011-06-14 US claimed
US-7884059-B2 Reaction product of a hydroxyaromatic compound, an aldehyde, an N-hydroxyethyl substituted diamine, and a molybdenum source AFTON CHEMICAL CORPORATION (US) 2011-02-08 US claimed
US-20060084584-A1 Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted mannich bases AFTON CHEMICAL CORPORATION 2006-04-20 US claimed
EP-0207864-B1 BINDERS FOR MANUFACTURE OF PRECISION CASTING MOLDS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-05-08 EP claimed
EP-0255441-B1 BINDER FOR MANUFACTURE OF PRECISION CASTING MOLD NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-04-11 EP claimed
US-4769076-A Binders for manufacture of precision casting molds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-06 US claimed
US-4769075-A METAL AMINOALKOXIDE, ALKYL SILICATE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-06 US claimed
EP-0207864-A2 Binders for manufacture of precision casting molds NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-01-07 EP claimed
US-7960321-B2 Reaction product of a hydroxyaromatic compound, an aldehyde, an N-hydroxyethyl substituted diamine, and a molybdenum source AFTON CHEMICAL CORPORATION (US) 2011-06-14 US disclosed
US-7884059-B2 Reaction product of a hydroxyaromatic compound, an aldehyde, an N-hydroxyethyl substituted diamine, and a molybdenum source AFTON CHEMICAL CORPORATION (US) 2011-02-08 US disclosed
US-20090075849-A1 OIL-SOLUBLE MOLYBDENUM DERIVATIVES DERIVED FROM HYDROXYETHYL-SUBSTITUTED MANNICH BASES AFTON CHEMICAL CORPORATION 2009-03-19 US disclosed
EP-1661967-B1 Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted Mannich bases AFTON CHEMICAL CORP (US) 2008-01-09 EP disclosed
EP-1661967-A1 Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted Mannich bases Afton Chemical Corporation (US) 2006-05-31 EP disclosed
US-20060084584-A1 Oil-soluble molybdenum derivatives derived from hydroxyethyl-substituted mannich bases AFTON CHEMICAL CORPORATION 2006-04-20 US disclosed
EP-0207864-B1 BINDERS FOR MANUFACTURE OF PRECISION CASTING MOLDS NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1991-05-08 EP disclosed
EP-0255441-B1 BINDER FOR MANUFACTURE OF PRECISION CASTING MOLD NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1990-04-11 EP disclosed
US-4769076-A Binders for manufacture of precision casting molds NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-06 US disclosed
US-4769075-A METAL AMINOALKOXIDE, ALKYL SILICATE NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 1988-09-06 US disclosed
EP-0255441-A2 Binder for manufacture of precision casting mold NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1988-02-03 EP disclosed
EP-0207864-A2 Binders for manufacture of precision casting molds NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1987-01-07 EP disclosed