SCHEMBL12438745

SCHEMBL12438745

COc1ccc(C2(c3ccc(OC(C)=O)c(C4CCCCC4)c3)CCCCC2)cc1C1CCCCC1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 5/20 0.43
LMNA P02545 1/20 0.42
SELP P16109 4/20 0.42
SELL P14151 3/20 0.42
NR3C1 P04150 1/20 0.40
PTGDR Q13258 2/20 0.40
PPARA Q07869 1/20 0.39
TSHR P16473 2/20 0.39
CASP1 P29466 1/20 0.39
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
MAPT P10636 1/20 0.38
MAPK1 P28482 1/20 0.38
HPGD P15428 1/20 0.37
PDE4A P27815 1/20 0.37
PDE4B Q07343 1/20 0.37
PDE4C Q08493 1/20 0.37
PDE4D Q08499 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10112728 0.89 PTGDR2 (0.42) PTGDR2LMNASELPSELLPTGDR
SCHEMBL14173050 0.84 PTGDR2 (0.40) PTGDR2LMNAPTGDRPPARA
SCHEMBL13054808 0.80 PTGDR2 (0.44) PTGDR2LMNASELPSELLPTGDR
SCHEMBL14173046 0.80 PTGDR2 (0.38) PTGDR2SELPSELLPTGDRPPARA
SCHEMBL26009186 0.79 PPARA (0.54) LMNANR3C1PPARATSHRCASP1
SCHEMBL26009188 0.79 PPARA (0.54) LMNANR3C1PPARATSHRCASP1
SCHEMBL804639 0.79 PPARA (0.54) LMNANR3C1PPARATSHRCASP1
SCHEMBL12438735 0.78 PTGDR2 (0.46) PTGDR2NR3C1PTGDRTSHRMEN1
SCHEMBL12438744 0.78 LMNA (0.46) LMNANR3C1PPARATSHRCASP1
SCHEMBL17084644 0.77 PPARA (0.52) LMNANR3C1PPARATSHRCASP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8396399-B2 Toner bearing member, developing device, image forming apparatus, and image forming method RICOH COMPANY, LTD. (JP) 2013-03-12 US disclosed
US-8369755-B2 Developing device and image forming apparatus using the developing device RICOH COMPANY, LTD. (JP) 2013-02-05 US disclosed
US-20110176835-A1 TONER BEARING MEMBER, DEVELOPMENT DEVICE, AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD (JP) 2011-07-21 US disclosed
US-20100329748-A1 DEVELOPING DEVICE AND IMAGE FORMING APPARATUS USING THE DEVELOPING DEVICE RICOH COMPANY, LTD. (JP) 2010-12-30 US disclosed
US-20100303509-A1 Toner Bearing Member, Developing Device, Image Forming Apparatus, And Image Forming Method RICOH COMPANY, LTD. (JP) 2010-12-02 US disclosed
US-20080146759-A1 Sulfur-Containing Compound, Method for Producing Same, Sulfur-Containing Polymer, and Optical Material IDEMITSU KOSAN CO., LTD (JP) 2008-06-19 US disclosed