Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | HTT | P42858 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | TLR2 | O60603 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.46 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.46 |
| ▸ | SRC | P12931 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1276592 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL30972130 | 0.88 | ALDH1A1 (0.79) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL3825898 | 0.86 | ALDH1A1 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL1665307 | 0.85 | ALDH1A1 (0.81) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL3235018 | 0.84 | ALDH1A1 (0.62) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL22804095 | 0.84 | TLR2 (0.50) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL3214106 | 0.84 | ALDH1A1 (0.47) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL2810260 | 0.83 | ALDH1A1 (0.71) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL23633015 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 | |
| SCHEMBL13035548 | 0.82 | ALDH1A1 (0.46) | ALDH1A1HPGDHTTSMN1; SMN2PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 235 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116903570-A | Preparation method of 7,3 (2 ', 4') -trihydroxy-5-methoxy-6-isopentenyl coumarin | 美迪西普瑞生物医药科技(上海)有限公司 | 2023-10-20 | — | — | CN | claimed |
| CN-116730808-A | Preparation method of cefvicin derivative intermediate | 重庆汉佩生物科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116731039-A | Process for the preparation of cephalosporin derivatives | 重庆汉佩生物科技有限公司 | 2023-09-12 | — | — | CN | claimed |
| CN-116514759-A | Synthesis method of dihydromyricetin | 华中农业大学 | 2023-08-01 | — | — | CN | claimed |
| CN-116270576-A | Application of polysubstituted benzene compounds in preparation of medicines for treating cognitive impairment diseases, structure and preparation method | 中国医学科学院医药生物技术研究所 | 2023-06-23 | — | — | CN | claimed |
| CN-113620919-A | Mechanical ball-milling auxiliary synthesis method of 2-amino-3-cyano-4H-pyran compounds | 浙江工业大学 | 2021-11-09 | — | — | CN | claimed |
| WO-2025202022-A9 | ANTICANCER MACROCYCLIC QUINAZOLINE-BASED INHIBITORS OF THE INERACTION BETWEEN RAS AND SOS1 | BAYER AKTIENGESELLSCHAFT (DE) | 2025-12-26 | — | — | WO | disclosed |
| WO-2025202022-A1 | ANTICANCER MACROCYCLIC QUINAZOLINE-BASED INHIBITORS OF THE INERACTION BETWEEN RAS AND SOS1 | BAYER AKTIENGESELLSCHAFT (DE) | 2025-10-02 | — | — | WO | disclosed |
| CN-119504685-A | Benzopyran flavonoid compound, preparation method and application thereof, and pharmaceutical preparation | 南开大学 | 2025-02-25 | — | — | CN | disclosed |
| US-20240166669-A1 | QUINAZOLINE AMINE DERIVATIVES AS KRAS INHIBITORS | NIKANG THERAPEUTICS, INC. | 2024-05-23 | — | — | US | disclosed |
| CN-117897145-A | Composition for treating or preventing obesity or obesity-related liver diseases comprising verbenone derivatives | 韩国新丰制药株式会社 | 2024-04-16 | — | — | CN | disclosed |
| CN-115636742-B | Recrystallization method | 江西亚太科技发展有限公司 | 2024-04-09 | — | — | CN | disclosed |
| CN-117693507-A | Inhibitor compounds | 奈奥芬莱有限公司 | 2024-03-12 | — | — | CN | disclosed |
| US-4999448-A | ALKYLATION WITH PHENYLTHIOMETHYL LITHIUM COMPOUND, CYCLIZATION, INTERMEDIATES FOR HERBICIDES | THE DOW CHEMICAL COMPANY (US) | 1991-03-12 | — | — | US | disclosed |
| EP-0403026-A1 | 12-Substituted-12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids, herbicidal compositions, and a method of controlling undesirable vegetation | DowElanco (US) | 1990-12-19 | — | — | EP | disclosed |
| US-4938790-A | Herbicidal 12-substituted 12H-dibenzo(D,G)(1,3)dioxocin-6-carboxylic acids | THE DOW CHEMICAL COMPANY (US) | 1990-07-03 | — | — | US | disclosed |
| US-4722931-A | MUSCLE RELAXANTS | LABORATORIOS DELAGRANGE (ES) | 1988-02-02 | — | — | US | disclosed |
| CN-86100669-A | The synthetic organic polymers that is used for selective flocculating floatation of titanium and iron ores | — | 1987-08-05 | — | — | CN | disclosed |
| EP-0158211-A2 | 1,4-Dihydropyridin derivatives, process for their preparation and their uses as medicaments | LABORATORIOS DELAGRANGE S.A. (ES) | 1985-10-16 | — | — | EP | disclosed |
| EP-0034754-A1 | 2-((3-amino-2-hydroxy-propoxy)-styryl) isoxazoles, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240166669-A1 | QUINAZOLINE AMINE DERIVATIVES AS KRAS INHIBITORS | KRAS, NRAS, HRAS | ALDH1A1 3856/4885HPGD 1524/4885HTT 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.