SCHEMBL12439724

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2320748	0.93	MET (0.40)	KDRCCNCCDK8CDK19MAPK1
	SCHEMBL13968474	0.91	KDR (0.36)	PAICSKDRCCNCCDK8CDK19
	SCHEMBL2321729	0.91	MAPK1 (0.42)	KDRMAPK1FGFR1JAK2JAK1
	SCHEMBL19791324	0.88	MAPK1 (0.39)	KDRMAPK1FGFR1
	SCHEMBL12440239	0.86	MET (0.40)	KDRCCNCCDK8CDK19MAPK1
	SCHEMBL2327513	0.86	MET (0.42)	METTGFBR1ABL1
	SCHEMBL2327583	0.85	MET (0.41)	KDRCCNCCDK8CDK19MAPK1
	SCHEMBL13968291	0.85	MET (0.39)	KDRCCNCCDK8CDK19MAPK1
	SCHEMBL2328404	0.84	MET (0.42)	KDRCCNCCDK8CDK19MAPK1
	SCHEMBL12440010	0.84	MAPK1 (0.44)	KDRMAPK1FGFR1TGFBR1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.