SCHEMBL12440239

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2320748	0.93	MET (0.40)	METCYP11B2KDRWNT1AURKB
	SCHEMBL2327583	0.92	MET (0.41)	METTGFBR1MAP4K4CYP11B2KDR
	SCHEMBL13968291	0.92	MET (0.39)	METTGFBR1MAP4K4CYP11B2KDR
	SCHEMBL2365126	0.90	BRAF (0.38)	METCYP11B2KDRCCNCCDK8
	SCHEMBL2324722	0.90	CYP11B2 (0.40)	TGFBR1MAP4K4CYP11B2KDRFGFR1
	SCHEMBL13968290	0.89	MET (0.37)	METTGFBR1MAP4K4CYP11B2KDR
	SCHEMBL13968474	0.87	KDR (0.36)	METTGFBR1MAP4K4CYP11B2KDR
	SCHEMBL2321729	0.87	MAPK1 (0.42)	MAP4K4CYP11B2KDRFGFR1MAPK1
	SCHEMBL13835189	0.86	NTRK1 (0.44)	METTGFBR1MAP4K4MAPK1
	SCHEMBL12439724	0.86	PAICS (0.37)	METTGFBR1KDRFGFR1CCNC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.