SCHEMBL12439728

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2324592	0.92	LMNA (0.36)	MAPTTHRBGSK3BCYP1A2CYP3A4
	SCHEMBL12440268	0.85	CNR2 (0.41)	MAPTGAALMNATSHR
	SCHEMBL12440279	0.85	DRD4 (0.39)	DRD4DRD2ADRA2AHTR2AKDM1A
	SCHEMBL2327284	0.84	CHEK1 (0.43)	DRD4DRD2KDM1A
	SCHEMBL2324168	0.82	ALK (0.42)	CLK4
	SCHEMBL12440774	0.82	HRH4 (0.41)	DRD4DRD2KDM1A
	SCHEMBL12441202	0.82	RPS6KA3 (0.43)	MAPTGAADRD4DRD2LMNA
	SCHEMBL12440009	0.82	ALDH1A1 (0.38)	DRD4DRD2CYP1A2CYP3A4CYP2D6
	SCHEMBL12440014	0.82	HRH4 (0.44)	MAPTDRD4DRD2ADRA2AHTR2A
	SCHEMBL12441212	0.82	NPC1 (0.39)	DRD4DRD2CYP1A2CYP3A4CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.